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To the best of our knowledge, the present study is the first to show that uric acid affected NO levels in VSMCs in a dose- and time-independent manner, while also providing comprehensive evidence that uric acid increased superoxide anion levels at 1, 3, 6, 12 and 24 h, with a less pronounced increase at 3 h compared with the other time points, and its dose-dependent effects on protein carbonyl levels

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Please keep the vial away from sunlight and avoid shaking it